Il tema musicale della serie è composto da Thomas Newman; la musica originale dello show è composta inoltre da Bobbie Gentry ("Fancy") , Richard Marvin , Shuggie Otis ("Inspiration Information") e Chris Seefried.

Sono in commercio due CD musicali contenenti la soundtrack ufficiale della serie.

Six Feet Under - Music from the HBO orginal series

Track Listings
1. Six Feet Under Title Theme - Thomas Newman
2. Heaven - Lamb
3. Deep Down & Dirty - Stereo MC's
4. I Love Being Here With You - Peggy Lee
5. One Time Too Many - PJ Harvey
6. Squares - The Beta Band
7. Distractions - Zero 7
8. Inspiration/Information - Shuggie Otis
9. Pure & Easy - The Dining Rooms
10. Let's Go Out Tonight - Craig Armstrong (feat. Paul Buchanan)
11. Spooky - Classics IV
12. Bohemian Like You - The Dandy Warhols
13. Mis Dos Pequenas - Orlando Cachaito Lopez
14. Waiting (Tom Lord-Alge Remix) - Devlins
15. Six Feet Under Title Theme (Rae & Christian Remix) - Thomas Newman
16. Six Feet Under Title Theme (Photek Remix) - Thomas Newman

Six Feet Under, Vol. 2: Everything Ends 

Track Listings
1. Feelin' Good - Nina Simone
2. Amazing Life - Jem (exclusive track)
3. Everything Is Everything - Phoenix
4. A Rush Of Blood To The Head - Coldplay
5. Breathe Me - Sia
6. Lucky - Radiohead
7. Time Is On My Side - Irma Thomas
8. Angajou (The Latin Project Remix) - Bebel Gilberto
9. Direction - Interpol (exclusive track)
10. Don't Fear The Reaper - Caesars (exclusive track)
11. Transatlanticism - Death Cab For Cutie
12. Cold Wind - The Arcade Fire (exclusive track)
13. Lonely Little Petunia - Imogen Heap